All of Us and COVID N3C

All of Us Program

The All of Us Research program, organized by the National Institutes of Health, is a prospective, multi-center observational study. Its goal is to create a centralized data repository from physical exams, surveys, electronic health records and -omic data to support secondary research and genome-wide association studies. A major aim of the program is to advance genome-wide and related association studies.

Participation

As of 2025, about 600,000 participants have contributed data, with roughly 300,000 linked to electronic health records.

Access

Researchers gain access after completing online training and credential verification. New users receive a quota of free compute time, typically sufficient for analysis that exclude -omic data.

COVID N3C Program

The COVID N3C is a collaboration among Clinical and Transactional Science Awards Program hubs, supported by the National Center for Advancing Translational Sciences.

Areas of Support

• Streamline COVID-19 clinical data analysis to improve efficiency and accessibility

• Advance knowledge of COVID-19 through collaborative research

• Showcase a new model for collaborative data sharing